Scope Venue Agenda Deadlines Organisers Sponsors Partners
Programme

 Tuesday, November 30 - Welcome & Opening
 09:00 - 14:00 Exhibition set-up
 15:00 - 17:00
Opening of the registration desk
 16:00 - 17:00 WELCOME RECEPTION
 SESSION I - Overview - Natural Peptides To Drugs
 17:00 - 17:15 Opening ceremony & Welcome notes
 17:15 - 18:00 Opening Lecture:  Prof. Robin OFFORD
Geneva University Medical School, Switzerland

Improving on nature: therapeutic enhancement of polypeptides
 18:00 - 19:30

Prof. Hans Vogel
University of Calgary, Alberta, Canada
Potential use of antimicrobial peptides as future antibiotics

  Dr Adriano Pimenta
Federal University of Minas Gerais, Belo Horizonte, Brazil
Small peptides, big world: prospecting, characterizing and optimizing structures of some neglected bioactive peptides from arthropod venoms
  Dr Corina Borghouts-Heinz
Georg Speyer Haus, Institute for Biomedical Research, Frankfurt am Main, Germany
Interference with crucial signaling events in cancer cells by peptide aptamers and targeted protein degradation vehicles (TPDV)
  Prof. Michael J. Tyler
Department of Environmental Biology, University of Adelaide, South Australia
Frog peptides in modern and historical use
  Dr Marina Rautenbach
Department of Biochemistry, University of Stellenbosch, Matieland, South Africa
Antifungal peptides with haemolytic activity directed against Plasmodium falciparum
 

Dr Sophie Michalet
Atheris Laboratories, Geneva, Switzerland
In vivo pharmacokinetic and pharmacodynamic studies of peptide drugs by mass spectrometry

  Dr Charlotte Hummer Vad
Novozymes A/S, Bagsvćrd, Denmark
Unlocking the magic of nature - Development and discovery of a new class of antimicrobial compounds
 20:00 - SWISS-EVENT DINNER
 Wednesday, December 1 - From Natural Peptides
 SESSION II - Toxins, Antimicrobial Peptides & Hormones
 8:30 - 9:15

Invited Lecture: Prof. Paul ALEWOOD
University of Queensland, Australia
Drugs from venoms

 9:15 - 10:00

Invited Lecture: Prof. Bob HANCOCK
University of British Columbia, Vancouver, Canada
Cationic host defence peptides as antibiotics and modulators of innate immunity

 10:00- 10:30 COFFEE BREAK & POSTERS
 10:30 - 11:15

Invited Lecture: Prof. Tomas GANZ
David Geffen School of Medicine at
UCLA, USA
Hepcidin, a new iron-regulatory and host-defense hormone

 11:15 - 11:50

Prof. Shigesada Higuchi
Showa University School of Pharmaceutical Sciences, Tokyo, Japan
Novel peptides from the ACEI/BPP-CNP precursor in crotaline snakes

  Dr Per Holse Mygind
Novozymes A/S, Bagsvćrd, Denmark
Characterization of plectasin - A novel antimicrobial defensin
 12:30 - 16:30 JOURNEY BY TRAIN TO GORNERGRAT MOUNTAIN (3'135 m)
LUNCH BREAK
OPEN AIR ACTIVITIES
 SESSION III - Therapeutic Targets & Mode of Action
 17:30 - 18:15

Invited Lecture: Prof. George CHANDY
University of  California Irvine, USA

Ion Channels in lymphocytes : therapeutic targets for autoimmune diseases

 18:15 - 18:50 Dr Ron Hogg
University of Geneva, Switzerland
Importance of natural peptides in the design of drugs targeted to ligand-gated ion channels
  Prof. Eefjan Breukink
Dept. Biochemistry of Membranes, Utrecht University, The Netherlands
The magic bullet nisin: structural insights and an additional mechanism of action?
 18:50 - 19:05 COFFEE BREAK
 19:05 - 20:30 Dr Vincent Dive
CEA, Centre d'Etude Nucleaires de Saclay, Gif/Yvette, France
ACE: Structure and Function - Insights from selective inhibitors
  Dr Arya Biragyn
GRC, National Institute on Aging, National Institutes of Health, Baltimore, USA
Beta-defensins as immunomodulator and vaccine carrier: Self-tumor antigens are cross-presented and rendered immunogenic through CCR6 when targeted to APCs as β-defensin fusions
  Prof. John Marchalonis
University of Arizona/ College of Medicine, Tucson, AZ, USA
Control of helper T cell polarization by T cell receptor derived peptides
  Prof.  Marguerite Kay
Institute for Biomedical Sciences and Technology, Temple, TX, USA
Physiologic autoantibodies and their neoantigens as therapeutic modalities
 

Dr Shubh Sharma
Palatin Technologies, Cranbury, NJ, USA

Metal-ion Induced Distinctive Array of Structures: A Novel Approach for Rational Design of Peptide Based Drugs

  Dr Philippe Favreau
Atheris Laboratories, Geneva, Switzerland
Venom proteomics and drug discovery: direct de novo sequencing of bioactive peptides from complex mixtures
 20:30 -  FREE EVENING
 Thursday, December 2 - Through Development
 SESSION IV - Structure-Function Studies & Modelling
 8:30 - 9:15 Invited Lecture: Prof. André MÉNEZ
CEA-Saclay, France
From Toxins to Drugs
 9:15 - 10:30 Dr Laszlo Otvos
OLPE, LLC, Audubon, PA, USA
Multifunctional antibacterial peptides
  Prof. Jon Nissen-Meyer
Department of Molecular Biosciences, University of Oslo, Norway
Structure-function analysis of the pediocin-like antimicrobial peptides: their three-dimensional structure, orientation in membranes, and domain functions
  Prof. Gopalakrishnakone Ponnampalam
National University of Singapore, Faculty of Medicine, Singapore
Anti-inflammatory peptides designed from phospholipase A2 inhibitory protein from the serum of python reticulates
  Dr Wim Jan Vrijbloed
Polyphor Ltd, Allschwil, Switzerland
Protein epitope mimetics (PEM) selectively targeting HIV-1 fusion events via the cellular coreceptor CXCR4
 10:30 - 11:00 COFFEE BREAK & POSTERS
 SESSION V - Drug Design & Delivery
 11:00 - 11:45 Invited Lecture: Prof. Richard DIMARCHI
Indiana University, USA
The Emergence of Chemical Biotechnology as a Means to Optimal Protein-Based Medicines
 11:45 - 12:40 Prof. David J. Craik
Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
The cyclic cystine knot as a scaffold for peptide drug delivery
  Prof. Paul Robert Hansen
Department of Natural Sciences, RVAU, Copenhagen, Denmark
Design, synthesis and characterization of novel antibacterial lysine-peptoid hybrids
  Dr Rinaldo Zurbriggen
Pevion Biotech, Berne, Switzerland
Peptides and peptidomimetics delivered by immunostimulating reconstituted influenza virosomes
 12:40 - 14:00

LUNCH BREAK

 14:00 - 17:00 OPTIONAL ACTIVITIES & NETWORKING SESSIONS
 SESSION VI - Production, Formulation & Manufacturing
 17:00 - 17:45 Invited Lecture: Dr Peter HOFFMANN
Genzyme Pharmaceuticals, USA
As Hannibal Delivered Elephants Across the Alps : Genzyme Delivers Peptides and Proteins Across the Blood Brain Barrier
 17:45 - 19:30

Dr Andy Strong
Dictagene, Lausanne, Switzerland
Fmoc synthesis of Interferon-alpha using long peptide thioesters prepared on a safety-catch resin

  Prof. Jin-Xing Wang
School of Life Sciences, Shandong University, Jinan, China
Molecular cloning, characterization and high level expression of shrimp antimicrobial peptides, Ch-penaeidins, in E. coli and Pichia pastoris
  Dr Michael Kleine
Planton GmbH, Kiel, Germany
Plant made pharmaceuticals (PMP)  –  A production system for anti-microbial peptides
  Prof. Keith Rose
Department of Structural Biology and Bioinformatics, University Medical Center, Geneva, Switzerland
Covalent capture – a useful purification process for synthetic and recombinant polypeptides
  Dr Reto Stöcklin
Atheris Laboratories, Geneva, Switzerland
A new affinity tag removal system in peptide synthesis and protein expression
  Dr Vincent Bille
UCB-Bioproducts, Belgium
Drug substance (API) and drug product manufacturing process development stages through late pre-clinical and clinical studies
 20:00 - GALA DINNER
 Friday, December 3 - To Clinics
 SESSION VII - Development & Clinical Trials
 8:30 - 9:15 Invited Lecture: Dr Stephen SCHNEIDER
Trimeris, USA
Development of the HIV Fusion Inhibitors Fuzeon and
T-1249
 9:15 - 10:30 Dr José de Chastonay
Bachem Americas, King of Prussia, PA, USA
The outlook for peptide drugs and the intricate relationship between the API manufacturer and their sponsor
  Dr Chandra Panchal
Procyon Biopharma Inc., Montreal, Canada
Development of a novel peptide drug PCK3145 derived from the naturally occurring prostate secretory protein PSP94
  Dr Thierry Abribat
Theratechnologies, Montreal, Quebec, Canada
Physiological peptides as drugs : the example of GHRH analogues
  Dr Shubh Sharma
Palatin Technologies, Cranbury, NJ, USA
PT-141: a melanotropin hormone analog for the treatment of sexual dysfunction
 10:30 - 11:00 COFFEE BREAK & POSTERS
 SESSION VIII - Route to Clinic
 11:00 - 11:45 Closing Lecture: Dr Timothy WELLS
Serono International, Switzerland
Biologics – the fast route to the clinic
 11:45 - 13:00 Roundtable: Peptides as Drugs: What for the Future ?
 13:00 - 13:10

Closing Notes

 13:10 - FAREWELL COCKTAIL / LUNCHEON

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