| Tuesday, November 30 - Welcome & Opening | |
| 09:00 - 14:00 | Exhibition set-up |
| 15:00 - 17:00 |
Opening of the registration desk |
| 16:00 - 17:00 | WELCOME RECEPTION |
| SESSION I - Overview - Natural Peptides To Drugs | |
| 17:00 - 17:15 | Opening ceremony & Welcome notes |
| 17:15 - 18:00 | Opening Lecture: Prof. Robin OFFORD Geneva University Medical School, Switzerland Improving on nature: therapeutic enhancement of polypeptides |
| 18:00 - 19:30 |
Prof. Hans Vogel |
| Dr Adriano Pimenta Federal University of Minas Gerais, Belo Horizonte, Brazil Small peptides, big world: prospecting, characterizing and optimizing structures of some neglected bioactive peptides from arthropod venoms | |
| Dr Corina Borghouts-Heinz Georg Speyer Haus, Institute for Biomedical Research, Frankfurt am Main, Germany Interference with crucial signaling events in cancer cells by peptide aptamers and targeted protein degradation vehicles (TPDV) | |
| Prof. Michael J. Tyler Department of Environmental Biology, University of Adelaide, South Australia Frog peptides in modern and historical use | |
| Dr Marina Rautenbach Department of Biochemistry, University of Stellenbosch, Matieland, South Africa Antifungal peptides with haemolytic activity directed against Plasmodium falciparum | |
|
Dr Sophie Michalet | |
| Dr Charlotte Hummer Vad Novozymes A/S, Bagsvćrd, Denmark Unlocking the magic of nature - Development and discovery of a new class of antimicrobial compounds | |
| 20:00 - | SWISS-EVENT DINNER |
| Wednesday, December 1 - From Natural Peptides | |
| SESSION II - Toxins, Antimicrobial Peptides & Hormones | |
| 8:30 - 9:15 |
Invited Lecture: Prof. Paul ALEWOOD |
| 9:15 - 10:00 |
Invited Lecture: Prof. Bob HANCOCK |
| 10:00- 10:30 | COFFEE BREAK & POSTERS |
| 10:30 - 11:15 |
Invited Lecture: Prof. Tomas GANZ |
| 11:15 - 11:50 |
Prof. Shigesada Higuchi |
| Dr Per Holse Mygind Novozymes A/S, Bagsvćrd, Denmark Characterization of plectasin - A novel antimicrobial defensin | |
| 12:30 - 16:30 | JOURNEY BY TRAIN TO GORNERGRAT MOUNTAIN (3'135 m) LUNCH BREAK OPEN AIR ACTIVITIES |
| SESSION III - Therapeutic Targets & Mode of Action | |
| 17:30 - 18:15 |
Invited Lecture: Prof. George CHANDY |
| 18:15 - 18:50 | Dr Ron Hogg University of Geneva, Switzerland Importance of natural peptides in the design of drugs targeted to ligand-gated ion channels |
| Prof. Eefjan Breukink Dept. Biochemistry of Membranes, Utrecht University, The Netherlands The magic bullet nisin: structural insights and an additional mechanism of action? | |
| 18:50 - 19:05 | COFFEE BREAK |
| 19:05 - 20:30 | Dr Vincent Dive CEA, Centre d'Etude Nucleaires de Saclay, Gif/Yvette, France ACE: Structure and Function - Insights from selective inhibitors |
| Dr Arya Biragyn GRC, National Institute on Aging, National Institutes of Health, Baltimore, USA Beta-defensins as immunomodulator and vaccine carrier: Self-tumor antigens are cross-presented and rendered immunogenic through CCR6 when targeted to APCs as β-defensin fusions | |
| Prof. John Marchalonis University of Arizona/ College of Medicine, Tucson, AZ, USA Control of helper T cell polarization by T cell receptor derived peptides | |
| Prof. Marguerite Kay Institute for Biomedical Sciences and Technology, Temple, TX, USA Physiologic autoantibodies and their neoantigens as therapeutic modalities | |
|
Dr Shubh Sharma | |
| Dr Philippe Favreau Atheris Laboratories, Geneva, Switzerland Venom proteomics and drug discovery: direct de novo sequencing of bioactive peptides from complex mixtures | |
| 20:30 - | FREE EVENING |
| Thursday, December 2 - Through Development | |
| SESSION IV - Structure-Function Studies & Modelling | |
| 8:30 - 9:15 | Invited Lecture: Prof. André MÉNEZ CEA-Saclay, France From Toxins to Drugs |
| 9:15 - 10:30 | Dr Laszlo Otvos OLPE, LLC, Audubon, PA, USA Multifunctional antibacterial peptides |
| Prof. Jon Nissen-Meyer Department of Molecular Biosciences, University of Oslo, Norway Structure-function analysis of the pediocin-like antimicrobial peptides: their three-dimensional structure, orientation in membranes, and domain functions | |
| Prof. Gopalakrishnakone Ponnampalam National University of Singapore, Faculty of Medicine, Singapore Anti-inflammatory peptides designed from phospholipase A2 inhibitory protein from the serum of python reticulates | |
| Dr Wim Jan Vrijbloed Polyphor Ltd, Allschwil, Switzerland Protein epitope mimetics (PEM) selectively targeting HIV-1 fusion events via the cellular coreceptor CXCR4 | |
| 10:30 - 11:00 | COFFEE BREAK & POSTERS |
| SESSION V - Drug Design & Delivery | |
| 11:00 - 11:45 | Invited Lecture: Prof. Richard DIMARCHI Indiana University, USA The Emergence of Chemical Biotechnology as a Means to Optimal Protein-Based Medicines |
| 11:45 - 12:40 | Prof. David J. Craik Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia The cyclic cystine knot as a scaffold for peptide drug delivery |
| Prof. Paul Robert Hansen Department of Natural Sciences, RVAU, Copenhagen, Denmark Design, synthesis and characterization of novel antibacterial lysine-peptoid hybrids | |
| Dr Rinaldo Zurbriggen Pevion Biotech, Berne, Switzerland Peptides and peptidomimetics delivered by immunostimulating reconstituted influenza virosomes | |
| 12:40 - 14:00 |
LUNCH BREAK |
| 14:00 - 17:00 | OPTIONAL ACTIVITIES & NETWORKING SESSIONS |
| SESSION VI - Production, Formulation & Manufacturing | |
| 17:00 - 17:45 | Invited Lecture: Dr Peter HOFFMANN Genzyme Pharmaceuticals, USA As Hannibal Delivered Elephants Across the Alps : Genzyme Delivers Peptides and Proteins Across the Blood Brain Barrier |
| 17:45 - 19:30 |
Dr Andy Strong |
| Prof. Jin-Xing Wang School of Life Sciences, Shandong University, Jinan, China Molecular cloning, characterization and high level expression of shrimp antimicrobial peptides, Ch-penaeidins, in E. coli and Pichia pastoris | |
| Dr Michael Kleine Planton GmbH, Kiel, Germany Plant made pharmaceuticals (PMP) – A production system for anti-microbial peptides | |
| Prof. Keith Rose Department of Structural Biology and Bioinformatics, University Medical Center, Geneva, Switzerland Covalent capture – a useful purification process for synthetic and recombinant polypeptides | |
| Dr Reto Stöcklin Atheris Laboratories, Geneva, Switzerland A new affinity tag removal system in peptide synthesis and protein expression | |
| Dr Vincent Bille UCB-Bioproducts, Belgium Drug substance (API) and drug product manufacturing process development stages through late pre-clinical and clinical studies | |
| 20:00 - | GALA DINNER |
| Friday, December 3 - To Clinics | |
| SESSION VII - Development & Clinical Trials | |
| 8:30 - 9:15 | Invited Lecture: Dr Stephen SCHNEIDER Trimeris, USA Development of the HIV Fusion Inhibitors Fuzeon and T-1249 |
| 9:15 - 10:30 | Dr José de Chastonay Bachem Americas, King of Prussia, PA, USA The outlook for peptide drugs and the intricate relationship between the API manufacturer and their sponsor |
| Dr Chandra Panchal Procyon Biopharma Inc., Montreal, Canada Development of a novel peptide drug PCK3145 derived from the naturally occurring prostate secretory protein PSP94 | |
| Dr Thierry Abribat Theratechnologies, Montreal, Quebec, Canada Physiological peptides as drugs : the example of GHRH analogues | |
| Dr Shubh Sharma Palatin Technologies, Cranbury, NJ, USA PT-141: a melanotropin hormone analog for the treatment of sexual dysfunction | |
| 10:30 - 11:00 | COFFEE BREAK & POSTERS |
| SESSION VIII - Route to Clinic | |
| 11:00 - 11:45 | Closing Lecture: Dr Timothy WELLS Serono International, Switzerland Biologics – the fast route to the clinic |
| 11:45 - 13:00 | Roundtable: Peptides as Drugs: What for the Future ? |
| 13:00 - 13:10 |
Closing Notes |
| 13:10 - | FAREWELL COCKTAIL / LUNCHEON |







