Programme

 Tuesday, April 18 -  Welcome & Opening

 09:00 - 14:00 Exhibition set-up
 14:00 - 17:00
Opening of the registration desk
 15:30 - 16:30 WELCOME RECEPTION
 SESSION I - Natural Peptides To Drugs
 16:30 - 16:45 Opening ceremony & Welcome notes
 16:45 - 17:30

Opening Lecture:  Prof. Geoffrey W. TREGEAR
Relaxin:
the journey from discovery to clinical trials
Howard Florey Institute, Australia

 17:30 - 19:10 Oral presentations
  Prof. Robin Offord

Using high technology to find simple solutions for developing countries
The Mintaka Foundation for Medical Research

 

Dr Maria Luisa Mangoni
Short host-defence peptides from frog skin

Universitŕ La Sapienza, Rome, Italy

  Dr David Deperthes

Substrate peptides for the development of protease inhibitors

Med Discovery SA, Geneva, Switzerland

  Prof. Sylvie Rebuffat

Siderophore-microcins, antimicrobial peptides with potent activity against Enterobacteriaceae: structure, biosynthesis and recognition
National Museum of Natural History, Paris, France

 

Dr Reto Stöcklin
Mass spectrometry mapping of Atheris snake venom reveals a new family of peptides
Atheris Laboratories, Geneva, Switzerland

 19:10 - 19:30 Hot-spot & lift presentations
  Dr Karine Puget

New natural peptides for GPCR de-orphanization
Genepep SA, Clapiers, France

  Dr Astrid Weiss

Survivin – an inhibitor of apoptosis as a target for peptide based therapy of human breast cancer

Georg Speyer Haus, Biomedical Research, Frankfurt am Main, Germany
  Dr Anne Fogli

Peptidomics and proteomics studies of transformed lymphocytes from patients with leukodystrophy
Atheris Laboratories, Geneva, Switzerland

  Prof. André Ménez
"Venomics" or : The venomous systems genome project
CEA-Saclay, France
 20:15 - SWISS-EVENT DINNER

 Wednesday, April 19 -  From Natural Peptides

 SESSION II - Genomics & Proteomics
 8:15 - 9:00

Invited Lecture: Dr Michael J. BROWNSTEIN
Venomics: A Primer
J. Craig Venter Institute, Rockville, USA

 9:00 - 10:00

Oral presentations

 !!! NEW !!!

Dr Shubh Sharma
From Peptides to Small Molecule Drug Candidates – Development of Melanotropin Receptor Ligands for the Treatment of Obesity
Palatin Technologies, Inc., Cranbury, USA

  Mrs Anna Perchuc & Dr Laure Menin

Structural and heparin-binding properties of two Bothrops moojeni phospholipases A2 and their derived C-terminal synthetic fragments
Pentapharm Ltd., Basel & Atheris Laboratories, Geneva, Switzerland

  Prof. Ponnampalam Gopalakrishnakone

Dual inhibitors of sPLA2 and MMP-1: A new potential therapeutic option for treatment of inflammation

National University of Singapore, Faculty of Medicine, Singapore
 10:00 - 10:30 COFFEE BREAK
 SESSION III - Drug Discovery
 10:30 - 11:15

Invited Lecture: Prof. Alan HARVEY
Protease-activated receptors as targets for anti-inflammatory drug discovery
Strathclyde Institute for Drug Research, UK

 11:15 - 11:50  Hot-spot presentations
  Dr Inna Radzishevsky
Structure-activity relationships in a novel class od antimicrobial pseudopeptides
Technion, Haifa, Israel
  Prof. Paul Alewood

Selenotoxins: A new chemical class of peptide drugs
University of Queensland, Australia

 

Dr Csaba Tömböly
Design and synthesis of 4-amino-1,2,4,5-tetrahydro-2-benzazepine-3-one containing endomorphin-2 mimetics
Institute of Biochemistry, Biological Research Center, Szeged, Hungary

 

Dr Peter Cassidy
The use of diastereomeric variation to produce peptide turn mimetics with low nanomolar affinity
Mimetica Pty, Ltd, Brisbane, Australia

 !!! NEW !!!

Prof. Alan Harvey
The International Society on Toxinology 2006 World Congress in Glasgow
Strathclyde Institute for Drug Research, UK

 

Title and speaker to be advised

 12:30 - 16:30

 

JOURNEY BY TRAIN TO GORNERGRAT MOUNTAIN (3'135 m)
LUNCH BREAK
OPEN AIR ACTIVITIES
 SESSION IV - Lead identification
 17:15 - 18:00

Invited Lecture: Dr Per Holse MYGIND
Plectasin, beyond nature – improving the natural peptide and developing a process for bioproduction
Novozymes A/S, Denmark

 18:00 - 18:55  Oral presentations
  Prof. David Craik
Structure and self association of the antiviral theta defensin
retrocyclin-2

University of Queensland, Brisbane, Australia
 

Dr Irmgard Irminger-Finger
BARD1, a promising target for selective cancer cell killing
University Hospitals Geneva HUG, Geneva Switzerland

  Dr Nicolas Gilles

A GPCR binding toxin as a new drug candidate against lower urinary track symptoms

CEA-Saclay, France
 18:55 - 19:15 COFFEE BREAK
 SESSION V - Lead optimisation
 19:15 - 20:00

Invited Lecture: Dr Alain BECK
Peptides as tools and drugs for immunotherapies
Centre d'Immunlogie Pierre Fabre, Saint-Julien, France

 20:00 - 20:40

Oral presentations

  Dr Jan Vrijbloed

POL7001, a novel and potent pseudomonal antibiotic protects mice in a septicemia model
Polyphor, Allschwil, Switzerland

  Dr Paul R. Hansen

Identification of antibacterial lysine-peptoid hybrids using a mixture-based combinatorial library

Royal Veterinary and Agricultural University, Copenhagen, Denmark

 20:40 - FREE EVENING

 Thursday, April 20 - Through Development

 SESSION VI - Drug design & Modelling
 8:30 - 9:15 Invited Lecture: Dr John P. MAYER
Melanocortin peptides for obesity
Eli Lilly and Co., Indianapolis, USA
 9:15 - 10:35

Oral presentations

  Dr Amram Mor

Novel antimicrobial peptidomimetics composed of acylated charged amino acids

Technion, Haifa, Israel
  Dr Emanuel Escher

Molecular structures, ligand binding and activation mechanisms for peptidergic G-protein coupled receptors for rational drug design
Faculté de Médecine et Sciences de la Santé, Sherbrooke, Canada

  Dr Marie Skovgaard

Using evolutionary information to understand the structure-sequence relationship of GLP-1 agonists

Novo Nordisk A/S, Maaloev, Denmark
  Prof. Anne Ulrich

Structure and function of membrane-active peptides by solid state NMR

University of Karlsruhe and Forschungszentrum Karlsruhe, Germany

 10:35 - 11:00 COFFEE BREAK & POSTERS
 SESSION VII - Production & Manufacturing
 11:00 - 11:45 Invited Lecture: Prof. Stephen B. H. KENT
Industrial chemical protein synthesis: what  will it take to make it happen?
University of Chicago, USA
 11:45 - 12:45

Oral presentations

  Dr Jon Nissen-Meyer

Structure and mode of action of the membrane-permeabilizing antimicrobial peptide pheromone plataricin A

University of Oslo, Norway
  Dr Luisa Bracci
Protease-resistant branched peptides as tumor targeting agents

University of Siena, Italy
  Prof. André Ménez
The same small three-fingered fold for human uPAR and toxins
CEA-Saclay, France
 12:45 - 14:00

LUNCH BREAK

 14:00 - 17:00 OPTIONAL ACTIVITIES & NETWORKING SESSIONS
 SESSION VIII - Formulation & Drug Delivery
 17:00 - 17:45 Invited Lecture: Dr Jennifer RIGGS-SAUTHIER
The art of PEGylation: advancing peptide drugs into the future
Nektar Therapeutics, Hunstville, USA
 17:45 - 19:05

Oral presentations

  Dr Corina Borghouts-Heinz

Peptides as inhibitors of signalling components in cancer cells

Georg Speyer Haus, Biomedical Research, Frankfurt am Main, Germany
  Dr Michel Geffard

Anti-bacterial activity of fatty acids linked on a polypeptide
Laboratory PIOM-EPHE, Pessac, France

  Dr Jorg Ronco

Evaluation of the E‑patch® technology for transcutaneous peptide delivery. MA320 model

DBV Technologies, Boulogne Billancourt, France
  Prof. Keith Rose

Multivalency – a way to enhance binding avidities and bioactivity – application to EPO

Department of Structural Biology and Bioinformatics, University of Geneva, Switzerland
 20:00 - GALA DINNER

 Friday, April 21 - To Clinics

 SESSION IX - Development & Clinical Trials
 8:30 - 9:15 Invited Lecture: Dr Patrick GARROUSTE
Debio Group, Switzerland
Key issues in the development of peptide drugs
 9:15 - 10:35

Oral presentations

  Dr Chandra Panchal

Evaluation of a prostate secretory protein94-derived synthetic peptide PCK3145 in patients with castrate metastatic prostate cancer: Inhibition of VEGF signaling, MMP-9 secretion and CD44-mediated MMP-9 cell surface binding

Ambrilia Biopharma, Verdun, Quebec, Canada
  Dr Thomas Dix

Non-natural arginine and lysine analogs in peptide drug development

Argolyn Bioscience, Inc., North Charleston, USA
  Dr Markwin Velders

Antimicrobial peptides; how good can they get ?

AM-Pharma, Bunnik, Netherlands
  Prof. Paul Alewood

Drug Discovery - where are we now and where are we going?

University of Queensland, Australia
 10:35 - 11:00 COFFEE BREAK
 SESSION X - Route to Clinic
 11:00 - 11:45 Closing Lecture: Dr George MILJANICH
PRIALTŇ (ziconotide intrathecal infusion): a conopeptide for treating severe chronic pain
Airmid LLC, USA
 11:45 - 13:00 Roundtable: Peptides Drugs : Mistakes to Avoid !
Four presentations by experts in intellectual property, funding, production & regulatory. Followed by an open debate.
  Dr Emmanuel Jelsch
Katzarov S.A., Switzerland 
  Dr Peter Hoffmann
Genzyme Pharmaceuticals, USA
  Dr Michel-Alain Mollard
SPEF Venture, France
  Dr Daniel Bourgin
Lonza, Switzerland
 13:00 - 13:10

Closing Notes

 13:10 - FAREWELL COCKTAIL / LUNCHEON



SPONSORS


EXHIBITORS



No Keywords
Powered by   v 3.9.6d  © 2002-2004 All rights reserved